All CUSP projects will produce data, for example on the properties of micro- and nanoplastics (MNPs), on actual human exposure levels, and on possible hazards at different exposure levels. But this means that a large amount of data will be generated in the cluster, and to make these data available for risk assessments of MNPs in the different projects, we need to develop a harmonized approach to data sharing across all CUSP projects. To achieve this, we collaborate in this working group on setting up a centralized data repository. As a first step, data management plans of all CUSP projects need be aligned according to FAIR principles (findability, accessibility, interoperability, and reusability), and in addition, data should be compared with regard to standardization of methods and outcome parameters. This data together will be of use to develop predictive models.